Biofilm infections
First time, researchers from Ohio State University designed electrical bandages can prevent bacterial biofilm infections, and battle against antibiotic resistance. The dressing active electrically upon contact with bodily fluids. Bacterial biofilm cells have high resistance in both antibiotics and host immune defenses.
“Drug resistance in bacteria is a major threat, and antibiotic-resistant biofilm infections estimate to account for at least 75% of bacterial infections in the United States,” said, Dr. Chandan Sen, director of Ohio State’s Center for Regenerative Medicine & Cell Based Therapies. This is the first study to recognize the possibility of ‘electroceuticals’ to fight against wound biofilm infection.
However, bacterial biofilms represent a major wound complication. Bacterial biofilm depends on electrostatic interactions, an important characteristic of biofilm formation.
Wireless electroceutical dressing
While previous studies, Sen designed a wireless electroceutical dressing (WED) using silver and zinc to print on fabric. Without any external power supply, the WED generates a weak electric field and can use like any other disposable dressing.
“Wireless electric dressing is FDA-cleared and already in clinical use heightens the need to understand the underlying mechanisms to enable optimal use,” Sen said.
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